There is a long tradition of charitable giving in the Choudhrie family, going back three generations and spanning three continents. Family members are brought up to believe they have a duty to give back to society, especially to those less fortunate than themselves.

In 1999, Sudhir Choudhrie received a life-saving heart transplant at Columbia University Medical Center in New York. Having lost his older brother Rajiv to the same condition in 1998, Sudhir and the other members of the Choudhrie became acutely aware of the need for further research and support in this area. Since then, the Choudhrie family has directly as well as through the Choudhrie Family Foundation, actively supported the advancement of medical science in the United States and abroad.

In 2005, the Choudhrie family started a series of donations to establish the Sudhir Choudhrie Professorship of Cardiology at the Columbia University Medical Center in New York. The Professorship has supported research into gene therapy and stem cell therapy to treat and ultimately find a cure for heart failure.

In 2010, the family founded the Choudhrie Family Foundation to steer and further their longstanding charitable initiatives in medicine, public health and education.